1-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropane → 2-Cyanomethyl-3-octadecylcarbamoyloxy-1-(3-iodopropylsulfonylamino)propane

HRID 728506Notes

Reaction equation

HRID 728506 reaction equation
Cl[CH2:2][CH2:3][CH2:4][S:5]([NH:8][CH2:9][CH:10]([CH2:34][C:35]#[N:36])[CH2:11][O:12][C:13](=[O:33])[NH:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])(=[O:7])=[O:6].C(SCC(OC)CNS(CCC[I:64])(=O)=O)CCCCCCCCCCCCCCC>>[C:35]([CH2:34][CH:10]([CH2:11][O:12][C:13](=[O:33])[NH:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:9][NH:8][S:5]([CH2:4][CH2:3][CH2:2][I:64])(=[O:7])=[O:6])#[N:36]

Participants

3

Reactant 2

HCID 148350231-Hexadecylthio-3-(3-iodopropylsulfonylamino)-2-methoxypropaneHCID 148350861-(3-Chloropropylsulfonylamino)-2-cyanomethyl-3-octadecylcarbamoyloxypropane

Product 1

HCID 148350872-Cyanomethyl-3-octadecylcarbamoyloxy-1-(3-iodopropylsulfonylamino)propane

Procedure

1-(3-Chloropropylsulfonylamino)-2-cyanomethyl-3-octadecylcarbamoyloxypropane IIIn2 is allowed to react by the same procedure as described in (5). The summary of the experimental condition and the physical data of the product are listed in Table 8.

Workup

  1. customto react by the same procedure

Sources & evidence

ORD record
ord-bb697a6dae7b4721a996196f7975bd93
Source dataset
uspto-grants-1991_09
Patent number
US05047540

Reaction notes

Loading…