HCID 12507348, compound → HCID 14127272, compound

HRID 728532Notes

Reaction equation

HRID 728532 reaction equation
[Cl:1][C:2]1([Cl:11])[C@@H:9]2[C@@H:4]([CH2:5][CH2:6][CH:7]=[CH:8]2)[C:3]1=[O:10].BrC1[C@@H]2[C@@H](CCC=C2)[C@H]1O.BrC1(Br)[C@@H]2[C@@H](CCC=C2)[C@H]1O>>[Cl:1][C:2]1([Cl:11])[C@@H:9]2[C@@H:4]([CH2:5][CH2:6][CH:7]=[CH:8]2)[C@H:3]1[OH:10]

Participants

3

Reactant 2

HCID 12507348HCID 12507348, compoundHCID 86745057HCID 86745057, compound

Product 1

HCID 14127272HCID 14127272, compound

Procedure

Similarly, following the procedure in paragraph 2.A. above, but substituting other ketones from Example 1 for (1S,6R)-8,8-dichlorobicyclo[4.2.0]oct-2-en-7-one, the following compounds of formula (6) are prepared: (1S,6R,7R)-8,8-dibromobicyclo[4.2.0]oct-2-en-7-ol (1S,6R,7R)-8-bromobicyclo[4.2.0]oct-2-en-7-ol

Sources & evidence

ORD record
ord-48d97bee7f0d44798c8b837f92c38373
Source dataset
uspto-grants-1991_09
Patent number
US05049497

Reaction notes

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