HCID 14127271, compound → HCID 12507348, compound

HRID 728534Notes

Reaction equation

HRID 728534 reaction equation
[Cl:1][C:2]1([Cl:11])[C@H:9]2[C@H:4]([CH2:5][CH2:6][CH:7]=[CH:8]2)[C@@H:3]1[OH:10].[Cl:12][C:13]1([Cl:22])[C@@H:20]2[C@@H:15]([CH2:16][CH2:17][CH:18]=[CH:19]2)[C@H:14]1[OH:21].BrC1[C@H]2[C@H](CCC=C2)C1=O.BrC1(Br)[C@H]2[C@H](CCC=C2)C1=O.BrC1[C@@H]2[C@@H](CCC=C2)C1=O.BrC1(Br)[C@@H]2[C@@H](CCC=C2)C1=O>>[Cl:1][C:2]1([Cl:11])[C@@H:9]2[C@@H:4]([CH2:5][CH2:6][CH:7]=[CH:8]2)[C:3]1=[O:10].[Cl:12][C:13]1([Cl:22])[C@H:20]2[C@H:15]([CH2:16][CH2:17][CH:18]=[CH:19]2)[C:14]1=[O:21]

Participants

5

Reactant 3

HCID 14127271HCID 14127271, compoundHCID 14127272HCID 14127272, compoundHCID 86745058HCID 86745058, compound

Product 2

HCID 12507348HCID 12507348, compoundHCID 12507349HCID 12507349, compound

Procedure

Similarly, following the procedure in paragraph 3.A. above, but starting with the compounds of formula (5) or (6), prepared as shown in Examples 1 and 2, the following compounds of formula (4) and (7) are prepared: (1S,6R)-8,8-dibromobicyclo[4.2.0]oct-2-en-7-one (1S,6R)-8-bromobicyclo[4.2.0]oct-2-en-7-one (1R,6S)-8,8-dibromobicyclo[4.2.0]oct-2-en-7-one (1R,6S)-8-bromobicyclo[4.2.0]oct-2-en-7-one

Workup

  1. customprepared

Sources & evidence

ORD record
ord-551bb70e5ee4482aaed6412d87916508
Source dataset
uspto-grants-1991_09
Patent number
US05049497

Reaction notes

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