HCID 14555866, compound → HCID 14555867, compound

HRID 728608Notes

Reaction equation

HRID 728608 reaction equation
C1C2C3C(=CC=CC=3)C(C=O)=CC=2SC=1.[CH:16]([C:18]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[C:21]2[S:22][C:23](C(OC)=O)=[CH:24][C:20]=2[CH:19]=1)=[O:17]>C(Cl)Cl.CCCCCC>[S:22]1[CH:23]=[CH:24][C:20]2[CH:19]=[C:18]([CH:16]=[O:17])[C:34]3[C:29]([C:21]1=2)=[CH:30][CH:31]=[CH:32][CH:33]=3

Participants

4

Reactant 2

HCID 14555866HCID 14555866, compoundHCID 14555900HCID 14555900, compound

Product 1

HCID 14555867HCID 14555867, compoundYield 61.9%

Reagents, catalysts & solvents 1

HCID 21226440Methylenechloride HexaneSolvent

Procedure

Using the procedure outlined in 7B, methyl naphtho[1,2-b]-thiophene-2-carboxylate (10A) gave a 61.9% yield of naphtho[1,2-b]thiophene-5-carbaldehyde, mp 96°-96.5°, (C,H,S), (CH2Cl2 /hexane).

Sources & evidence

ORD record
ord-524e9f3fdf914503bd72f1d1f9031362
Source dataset
uspto-grants-1991_09
Patent number
US05049581

Reaction notes

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