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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 728757Generated: October 30, 2026

1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)- → HCID 465659, compound

https://huagongshe.com/reaction/728757

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)-HCID 11325—
ReactantZidovudineHCID 35370—
ProductHCID 465659HCID 465659—

Reaction Steps

AZT is reacted with N-(2-bromoethyl)-phthalimide (Reaction B) to provide 3-(2-phthalimidoethyl)-3'-azido-3'-deoxythymidine (3-PHT-E-AZT) (Example 25).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05051361
Source datasetuspto-grants-1991_09
ORD IDord-58d9787fc2aa4ca0ba125a00f64c1953
Source noteuspto-grants-1991_09