Dichloromethane → HCID 67832220, compound

Participants

Reaction Steps

25.5 g (0.22 mole) of methanesulfonyl chloride were added dropwise, at 0°-5° C., to an initially taken mixture of 34 g (0.2 mole) of decalindiol and 30.3 g (0.3 mole) of triethylamine in 500 ml of dichloromethane. Stirring was then carried out for a further hour at room temperature. The mixture was poured onto ice, the organic phase was separated off and the aqueous phase was extracted several times with dichloromethane. The combined organic phases were washed with dilute hydrochloric acid, water and 5% strength sodium bicarbonate solution, dried over sodium sulfate and evaporated down under reduced pressure.

Provenance & Evidence