Isoniazid → HCID 178435134, compound

HRID 728787Notes

Reaction equation

HRID 728787 reaction equation
[CH3:1][CH:2]1[S:7][C:6](=[O:8])[NH:5][N:4]=[C:3]1[C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][C:13](=[O:18])[C:12]2=[N:19]C1C=CC=CC=1.[C:26]([NH:34]N)(=[O:33])[C:27]1[CH:32]=[CH:31][N:30]=[CH:29][CH:28]=1>>[CH3:1][CH:2]1[S:7][C:6](=[O:8])[NH:5][N:4]=[C:3]1[C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][C:13](=[O:18])[C:12]2=[N:19][NH:34][C:26]([C:27]1[CH:32]=[CH:31][N:30]=[CH:29][CH:28]=1)=[O:33]

Participants

3

Reactant 2

HCID 3767IsoniazidHCID 1357781391,3-dihydro-5-(3,6-dihydro-6-methyl-2-oxo-2H-1,3,4-thiadiazin-5-yl)-3-phenylimino-2H-indol-2-one

Product 1

HCID 178435134HCID 178435134, compoundYield 68%

Procedure

Starting from 1,3-dihydro-5-(3,6-dihydro-6-methyl-2-oxo -2H-1,3,4-thiadiazin-5-yl)-3-phenylimino-2H-indol-2-one, and isonicotinic acid hydrazide and following the method described in Example 21, the desired compound was obtained.

Sources & evidence

ORD record
ord-f98e6b6e3bf64f2fb897ce052fc5adfb
Source dataset
uspto-grants-1991_09
Patent number
US05051417

Reaction notes

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