(1-Benzylpyrrolidin-2-yl)methanol → 1-Benzyl-2-[[4-(1H-imidazol-1-yl)-1,2,5-thiadiazol-3-yloxy]methyl]pyrrolidine

HRID 728791Notes

Reaction equation

HRID 728791 reaction equation
Cl[C:2]1[C:6]([N:7]2[CH:11]=[CH:10][N:9]=[CH:8]2)=[N:5][S:4][N:3]=1.[CH2:12]([N:19]1[CH2:23][CH2:22][CH2:21][CH:20]1[CH2:24][OH:25])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[CH2:12]([N:19]1[CH2:23][CH2:22][CH2:21][CH:20]1[CH2:24][O:25][C:2]1[C:6]([N:7]2[CH:11]=[CH:10][N:9]=[CH:8]2)=[N:5][S:4][N:3]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 562951(1-Benzylpyrrolidin-2-yl)methanolHCID 156624193-chloro-4-(1H-imidazol-1-yl)-1,2,5-thiadiazole

Product 1

HCID 537575171-Benzyl-2-[[4-(1H-imidazol-1-yl)-1,2,5-thiadiazol-3-yloxy]methyl]pyrrolidine

Procedure

Following the procedures of Example 1, the title compound is prepared from 3-chloro-4-(1H-imidazol-1-yl)-1,2,5-thiadiazole and 1-benzyl-2-(hydroxymethyl)pyrrolidine.

Sources & evidence

ORD record
ord-70d96ced80224108b334e4904423ab11
Source dataset
uspto-grants-1991_09
Patent number
US05051420

Reaction notes

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