HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl chloroformate → S-[2-(diethylamino)ethyl]-S-[4-(1H-imidazol-1-yl)-1,2,5-thiadiazol-3-yl]-N-[(phenylmethoxy)carbonyl]sulfoximine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl chloroformate | HCID 10387 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | S-[2-(diethylamino)ethyl]-S-[4-(1H-imidazol-1-yl)-1,2,5-thiadiazol-3-yl]sulfoximine | HCID 57202344 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | S-[2-(diethylamino)ethyl]-S-[4-(1H-imidazol-1-yl)-1,2,5-thiadiazol-3-yl]-N-[(phenylmethoxy)carbonyl]sulfoximine | HCID 57032928 | — |
Reaction Steps
A mixture of S-[2-(diethylamino)ethyl]-S-[4-(1H-imidazol-1-yl)-1,2,5-thiadiazol-3-yl]sulfoximine (10 mmol), benzyl chloroformate (12 mmol) and potassium carbonate(32 mmol) in methylene chloride is stirred at ambient temperature for 5 hr.The mixture is filtered and the filtrate concentrated to obtain the productwhich is purified using standard laboratory procedures.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051420 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-c41b18febe164aeeac840781b348b8a2 |
| Source note | uspto-grants-1991_09 |