Sodium Hydroxide → HCID 53815284, compound

HRID 728823Notes

Reaction equation

HRID 728823 reaction equation
Cl.Cl.[N:3]1([C:8]2[CH:19]=[CH:18][C:11]([O:12][CH2:13][C:14]([CH3:17])([CH3:16])[NH2:15])=[CH:10][CH:9]=2)[CH:7]=[CH:6][N:5]=[CH:4]1.[OH-].[Na+]>O>[N:3]1([C:8]2[CH:19]=[CH:18][C:11]([O:12][CH2:13][C:14]([CH3:17])([CH3:16])[NH2:15])=[CH:10][CH:9]=2)[CH:7]=[CH:6][N:5]=[CH:4]1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 67689860HCID 67689860, compound

Product 1

HCID 53815284HCID 53815284, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Partially dissolve 30.69 g (0.1 mol) of 2-[4-(1H-imidazol-1-yl)phenoxy]-1,1-dimethylethanamine dihydrochloride in 50 mL of water and make basic with 70 mL 4 N NaOH. Extract this mixture with 2×100 mL of methylene chloride. Remove the solvent on a rotary evaporator to provide the title compound.

Workup

  1. extractionExtract this mixture with 2×100 mL of methylene chloride
  2. customRemove the solvent
  3. customon a rotary evaporator

Sources & evidence

ORD record
ord-435db6a38baa4bf1878d1de89c179ce1
Source dataset
uspto-grants-1991_09
Patent number
US05051423

Reaction notes

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