HCID 54426240, compound → HCID 14739909, compound

Participants

Reaction Steps

Dissolve 3.8 9 2-[[2-[4-(1H-imidazol-1-yl)phenoxy]ethyl](phenylmethyl)amino]-1-(2-methoxyphenyl)ethanone in 50 mL 5 M HCl in methanol and remove the solvents in vacuo. Dissolve the residue in 50 mL H2O with 0.85 9 10% palladium hydroxide on charcoal. Hydrogenate the solution under 52 psi hydrogen for 20 h. After this time, filter the catalyst and remove the solvents to givethe crude product. Recrystallize the solid from ethanol to give the title compound.

Provenance & Evidence