Hydrochloric Acid → HCID 88508788, compound

Participants

Reaction Steps

1.5 g of E-2-amino-5-phosphono-3-pentenoic acid are suspended in 30 ml of sec.-butanol and the suspension is saturated with hydrogen chloride gasfor 4 hours at 75°. After concentration, the residue is dissolved in10 ml of 2-butanol, 10 ml of propylene oxide are added and the precipitate is filtered off. Recrystallisation from water/acetone 1:1 yields E-2-amino-5-phosphono-3-pentenoic acid sec.-butyl ester, m.p. 169°-170°.

Provenance & Evidence