HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxyaniline → N-(3-Methoxyphenyl)-N'-(phenylmethyl)-1,2-ethanediamine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxyaniline | HCID 10824 | — |
| Reactant | Benzenemethanamine, N-(2-chloroethyl)-, hydrochloride (1:1) | HCID 13054189 | — |
| Product | N-(3-Methoxyphenyl)-N'-(phenylmethyl)-1,2-ethanediamine hydrochloride | HCID 19755023 | — |
Reaction Steps
Combine 3-methoxybenzenamine (81.2 g, 0.66 mol) with N-(2-chloroethyl)-benzenemethanamine hydrochloride (45.3 g, 0.22 mol) and heat to 190° C. for 13 h. Add methylene chloride to precipitate a solid. Filter the solid and wash with methylene chloride. Triturate the solid with 100 mL of ethanol, filter the solid and wash with ethanol to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051422 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-ea00a29a82bd4dcab40ac011449b56ee |
| Source note | uspto-grants-1991_09 |