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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 728922Generated: October 30, 2026

4-(2-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinecarboxamide → 4-(2-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamine

https://huagongshe.com/reaction/728922

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinecarboxamideHCID 14998756—
ReactantAluminium lithium hydrideHCID 21226445—
Product4-(2-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamineHCID 14998772—

Reaction Steps

In a manner similar to Preparation 2, react 4-(2-methoxyphenyl)-1-(phenylmethyl)-2-piperazinecarboxamide (4.0 g, 16.6 mmol) with lithium aluminum hydride (1.0 g, 26 mmol) to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05051422
Source datasetuspto-grants-1991_09
ORD IDord-09ab32eb2f48491aa1e7cbab602ab0ed
Source noteuspto-grants-1991_09