Potassium Hydroxide → 4-(3-Aminophenyl)-2-piperazinecarboxylic acid

HRID 728939Notes

Reaction equation

HRID 728939 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([N:8]2[CH2:13][CH2:12][NH:11][CH:10]([C:14](N)=[O:15])[CH2:9]2)[CH:5]=[CH:6][CH:7]=1.[OH-:17].[K+]>>[NH2:1][C:2]1[CH:3]=[C:4]([N:8]2[CH2:13][CH2:12][NH:11][CH:10]([C:14]([OH:15])=[O:17])[CH2:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 149988184-(3-Aminophenyl)-2-piperazinecarboxamide

Product 1

HCID 149988194-(3-Aminophenyl)-2-piperazinecarboxylic acid

Procedure

In a manner similar to Preparation 17, react 4-(3-aminophenyl)-2-piperazinecarboxamide with potassium hydroxide to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 17

Sources & evidence

ORD record
ord-80b6480d68a143d686b7ce539535224f
Source dataset
uspto-grants-1991_09
Patent number
US05051422

Reaction notes

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