Veratrylamine → N-(3-Bromo-5-methoxyphenyl)-2-[[(3,4-dimethoxyphenyl)methyl]amino]acetamide

HRID 728952Notes

Reaction equation

HRID 728952 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([NH:10][C:11](=[O:14])[CH2:12]Cl)[CH:5]=[C:6]([O:8][CH3:9])[CH:7]=1.[CH3:15][O:16][C:17]1[CH:18]=[C:19]([CH2:25][NH2:26])[CH:20]=[CH:21][C:22]=1[O:23][CH3:24]>>[Br:1][C:2]1[CH:3]=[C:4]([NH:10][C:11](=[O:14])[CH2:12][NH:26][CH2:25][C:19]2[CH:20]=[CH:21][C:22]([O:23][CH3:24])=[C:17]([O:16][CH3:15])[CH:18]=2)[CH:5]=[C:6]([O:8][CH3:9])[CH:7]=1

Participants

3

Reactant 2

HCID 79832VeratrylamineHCID 14998829HCID 14998829, compound

Product 1

HCID 14998798N-(3-Bromo-5-methoxyphenyl)-2-[[(3,4-dimethoxyphenyl)methyl]amino]acetamide

Procedure

In a manner similar to Preparation 12, react N-(3-bromo-5-methoxyphenyl)-2-chloroacetamide with 3,4-dimethoxybenzenemethanamine to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 12

Sources & evidence

ORD record
ord-1ef0bc2e01ca4affb6dfa87e0c0777f5
Source dataset
uspto-grants-1991_09
Patent number
US05051422

Reaction notes

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