HCID 14998775, compound → HCID 14998831, compound

HRID 728957Notes

Reaction equation

HRID 728957 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][C:17]3[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[C:19]([O:25][CH3:26])[CH:18]=3)[CH:12]([CH2:27][NH2:28])[CH2:11]2)[CH:5]=[C:6]([O:8][CH3:9])[CH:7]=1.[N:29]1([C:34]2[CH:39]=[CH:38][C:37]([S:40](Cl)(=[O:42])=[O:41])=[CH:36][CH:35]=2)[CH:33]=[CH:32][N:31]=[CH:30]1>>[Br:1][C:2]1[CH:3]=[C:4]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][C:17]3[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[C:19]([O:25][CH3:26])[CH:18]=3)[CH:12]([CH2:27][NH:28][S:40]([C:37]3[CH:38]=[CH:39][C:34]([N:29]4[CH:33]=[CH:32][N:31]=[CH:30]4)=[CH:35][CH:36]=3)(=[O:41])=[O:42])[CH2:11]2)[CH:5]=[C:6]([O:8][CH3:9])[CH:7]=1

Participants

3

Reactant 2

HCID 14998775HCID 14998775, compoundHCID 149988304-(1H-Imidazol-1-yl)benzenesulfonyl chloride

Product 1

HCID 14998831HCID 14998831, compound

Procedure

In a manner similar to Preparation 3, react 4-(3-bromo-5-methoxyphenyl)-1-[(3,4-dimethoxyphenyl)methyl]-2-piperazinemethanamine with 4-(1H-imidazol-1-yl)benzenesulfonyl chloride to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 3

Sources & evidence

ORD record
ord-ed71e40d35634d618a760f72e5f6de8b
Source dataset
uspto-grants-1991_09
Patent number
US05051422

Reaction notes

Loading…