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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 728968Generated: November 1, 2026

4-(4-Ethoxyphenyl)-N-(2-methoxyethyl)-N-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-1-(phenylmethyl)-2-piperazinecarboxamide → 4-(4-Ethoxyphenyl)-N-(2-methoxyethyl)-N-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-1-(phenylmethyl)-2-piperazinemethanamine

https://huagongshe.com/reaction/728968

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Ethoxyphenyl)-N-(2-methoxyethyl)-N-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-1-(phenylmethyl)-2-piperazinecarboxamideHCID 14998778—
ReactantAluminium lithium hydrideHCID 21226445—
Product4-(4-Ethoxyphenyl)-N-(2-methoxyethyl)-N-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-1-(phenylmethyl)-2-piperazinemethanamineHCID 14998779—

Reaction Steps

In a manner similar to Preparation 2, react 4-(4-ethoxyphenyl)-N-(2-methoxyethyl)-N-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-1-(phenylmethyl)-2-piperazinecarboxamide with lithium aluminum hydride to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05051422
Source datasetuspto-grants-1991_09
ORD IDord-ace845a8f1134b9e8cbb461d94ec7ba8
Source noteuspto-grants-1991_09