2,3-Dibromopropionamide → 1-Methyl-4-phenyl-2-piperazinecarboxamide

HRID 728972Notes

Reaction equation

HRID 728972 reaction equation
[CH3:1][NH:2][CH2:3][CH2:4][NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.Br[CH:13]([CH2:17]Br)[C:14]([NH2:16])=[O:15]>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=2)[CH2:17][CH:13]1[C:14]([NH2:16])=[O:15]

Participants

3

Reactant 2

HCID 857982,3-DibromopropionamideHCID 10582940Methyl[2-(phenylamino)ethyl]amine

Product 1

HCID 149987691-Methyl-4-phenyl-2-piperazinecarboxamide

Procedure

In a manner similar to preparation 1, react N-methyl-N'-phenyl-1,2-ethanediamine with 2,3-dibromopropanamide to obtainthe title compound.

Workup

  1. customIn a manner similar to preparation 1

Sources & evidence

ORD record
ord-5d87b3ec1677429797f935ed4b63be97
Source dataset
uspto-grants-1991_09
Patent number
US05051422

Reaction notes

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