HCID 14998845, compound → HCID 14998867, compound

HRID 728987Notes

Reaction equation

HRID 728987 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][CH3:16])[CH:11]([C:17]([NH:19][C:20]3[CH:25]=[CH:24][C:23]([N:26]4[CH:30]=[CH:29][N:28]=[CH:27]4)=[CH:22][CH:21]=3)=O)[CH2:10]2)[CH:5]=[CH:6][C:7]=1[Cl:8].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][CH3:16])[CH:11]([CH2:17][NH:19][C:20]3[CH:25]=[CH:24][C:23]([N:26]4[CH:30]=[CH:29][N:28]=[CH:27]4)=[CH:22][CH:21]=3)[CH2:10]2)[CH:5]=[CH:6][C:7]=1[Cl:8]

Participants

3

Reactant 2

HCID 14998845HCID 14998845, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 14998867HCID 14998867, compound

Procedure

In a manner similar to preparation 2, react 4-(3,4-dichlorophenyl)-1-ethyl-N-[4-(1H-imidazol-1-yl)phenyl]-2-piperazinecarboxamide with lithium aluminum hydride to obtain the title compound.

Workup

  1. customIn a manner similar to preparation 2

Sources & evidence

ORD record
ord-b19c2854de5a48b0afd343f6825a1006
Source dataset
uspto-grants-1991_09
Patent number
US05051422

Reaction notes

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