HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → 3-[(Carbethoxymethyl)sulfinyl]-2-carbethoxyindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | 3-[(Carbethoxymethyl)thio]-2-carbethoxyindole | HCID 15008209 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-[(Carbethoxymethyl)sulfinyl]-2-carbethoxyindole | HCID 54089258 | — |
Reaction Steps
3-[(Carbethoxymethyl)thio]-2-carbethoxyindole is treated with m-chloroperbenzoic acid (1 eq.) in methylene chloride at 0° C. The reaction is followed by TLC. After starting material is consumed the reaction mixture is washed with sat. NaHCO3 and sat. NaCl. The organic layer is dried. 3-[(Carbethoxymethyl)sulfinyl]-2-carbethoxyindole may be isolated by flash column chromatography followed by recrystallization.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051442 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-ec486214e05345d89715316f463f0fc7 |
| Source note | uspto-grants-1991_09 |