反应详情

A mixture of 0.75 g (2.07 mmol) of (4-(4-(2-quinolinylmethyloxy)styryl)benzonitrile and 0.08 g of 10% Pd on carbon in 75 ml of ethanol is shaken for 1.5 hours under 30 PSI of hydrogen. The mixture is filtered through a bed of celite and the filtrateconcentrated in vacuo. Trituration with ether gives a precipitate which is filtered off and recrystalized from methylene chloride-ether to give 4-(4-(2-quinolinylmethyloxy)phenethyl)benzonitrile. (M.P. 156° C.-158° C.)

1. filtrationThe mixture is filtered through a bed of celite
2. customTrituration with ether gives a precipitate which
3. filtrationis filtered off
4. customrecrystalized from methylene chloride-ether