HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 14800776, compound → HCID 14800777, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 14800776 | HCID 14800776 | — |
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 14800777 | HCID 14800777 | — |
Reaction Conditions
| Temperature | 0 °C |
|---|
Reaction Steps
A solution of diisobutyl aluminum hydride (0.01 mol) in hexane is added dropwise to a solution of methyl 3-(3-(2-quinolinylmethyloxy)benzyl)benzoate (0.01 mol) in 100 ml of THF at0° C. The reaction mixture is stirred at 0° C. for 30 minutesand then quenched with methanol and Rochelle salt. Extraction with ethyl acetate and purified by column chromatography gives 3-(3-(2-quinolinylmethyloxy)benzyl)benzaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051427 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-fcb037d114e84e4c88076d386d48a3a2 |
| Source note | uspto-grants-1991_09 |