Water → HCID 68932463, compound

Participants

Reaction Steps

Acetic anhydride (59 g, 0.58 mol) was mixed with pyridine (50 g) and Product A (72 g, 0.58 mol) added slowly with stirring and cooling to prevent the temperature exceeding 50° C. The mixture was allowed to stand overnight at room temperature and then poured into a large excess of cold water. Diethyl ether was added and the reaction product extracted then washed with water, 1% hydrochloric acid and again with water.

Provenance & Evidence