HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → HCID 15749831, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | 1-(2-Methylphenyl)-4-chloro-6-methylpyrrolo[3,2-c]quinoline | HCID 15749829 | — |
| Product | HCID 15749831 | HCID 15749831 | 72.2% |
Reaction Steps
1-(2-Methylphenyl)-4-chloro-6-methylpyrrolo[3,2-c]quinoline (1.0 g) and ethanolamine (3.0 g) were heated to 150° C. for 3 hours. Chromatography (silica gel, 2% methanolic ammonia in dichloromethane) and recrystallisation from ethyl acetate/petroleum ether yielded 1-(2-methylphenyl)-4-(2-hydroxyethylamino)-6methylpyrrolo[3,2-c]quinoline (0.78 g), m.p. 187°-188°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051508 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-2a63d8d7a4fe4e398974e194d60d99a6 |
| Source note | uspto-grants-1991_09 |