HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-1-butanol → HCID 67905905, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-1-butanol | HCID 25868 | — |
| Reactant | 1-(2-Methylphenyl)-4-chloro-6-methylpyrrolo[3,2-c]quinoline | HCID 15749829 | — |
| Product | HCID 67905905 | HCID 67905905 | 62% |
Reaction Steps
1-(2-methylphenyl)4 -chloro-6-methylpyrrolo[3,2-c]quinoline (1.0 g, 3,26 mmol) was dissolved in 4-aminobutanol (3.0 g) and stirred for 6 hoursat 170°. Chromatography (silica gel, 2% methanolic ammonia in dichloromethane), conversion to the hydrochloride and recrystallisation from ethanol/ether gave 1-(2-methylphenyl)-4-(4-hydroxybutylamino)-6-methylpyrrolo[3,2-c]quinolinehydrochloride (0.8 g), m.p. 176°-178°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05051508 |
| Source dataset | uspto-grants-1991_09 |
| ORD ID | ord-ac3ecae009c943adb70ee083935cd7b1 |
| Source note | uspto-grants-1991_09 |