Hydroxide → 865144-53-2

HRID 729200Notes

Reaction equation

HRID 729200 reaction equation
[I-].[OH-:2].[CH:3]1([N:9]2[CH2:14][CH2:13][N+:12]([CH3:16])([CH3:15])[CH2:11][CH2:10]2)[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1>O>[OH-:2].[CH:3]1([N:9]2[CH2:10][CH2:11][N+:12]([CH3:16])([CH3:15])[CH2:13][CH2:14]2)[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1

Participants

5

Reactant 3

HCID 961HydroxideHCID 30165Iodide Ion2×HCID 57610865HCID 57610865, compound

Product 1

HCID 67027446865144-53-2

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The iodide of the cation is exchanged for hydroxide using an ion exchange resin in accordance with the following procedure: 20 g (62 mmol) of the iodide of the cation (R′I) is dissolved in water. 62 g of Dowex SBR resin is added to the solution obtained and it is kept under stirring until the following day. Afterwards, it is filtered, washed with distilled water and a solution of 4-cyclohexyl-1,1-dimethyl-piperazinium hydroxide (R′OH) is obtained which is titrated with HCl (aq.) using phenolphthalein as indicator, obtaining an efficiency in the exchange of higher than 90%. The final solution contains 1 equivalent of hydroxide per 1000 g of solution.

Workup

  1. addition62 g of Dowex SBR resin is added to the solution
  2. customobtained
  3. filtrationAfterwards, it is filtered
  4. washwashed with distilled water

Sources & evidence

ORD record
ord-918158ed370745239fc456d3d92d1ec7
Source dataset
uspto-grants-2009_09
Patent number
US07582278B2

Reaction notes

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