P-Anisidine → HCID 11705786, compound

Participants

Reaction Steps

The title compound was prepared from 4-chloro-2-[4-(difluoromethoxy)benzyl]-5-phenylisothiazol-3(2H)-one 1,1-dioxide and 4-methoxyaniline in a similar manner as described for e.g. Examples 14 and 30. H NMR (400 MHz, CDCl3): δ 3.67 (s, 3H), 4.86 (s, 2H), 6.48-6.52 (m, 2H), 6.50 (t, J=74 Hz, 1H), 6.60-6.64 (m, 2H), 7.09-7.14 (m, 7H), 7.52-7.56 (m, 2H); 13C NMR (100 MHz, CDCl3): δ 42.8, 55.5, 109.9, 113.6, 115.8 (t, J=259 Hz), 119.6, 123.8, 124.6, 128.0, 128.7, 129.0, 129.3, 130.6, 131.3, 131.4, 151.2, 157.3, 159.3; Mass Spectrum: M−H+ 485.

Provenance & Evidence