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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 729308Generated: October 30, 2026

4-Cyclohexylbenzenamine → HCID 11619078, compound

https://huagongshe.com/reaction/729308

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-CyclohexylbenzenamineHCID 80764—
Reactant4-Chloro-2-(2-methoxyethyl)-5-phenylisothiazol-3(2H)-one 1,1-dioxideHCID 67243909—
ProductHCID 11619078HCID 11619078—

Reaction Steps

The title compound was prepared from 4-chloro-2-(2-methoxyethyl)-5-phenylisothiazol-3(2H)-one 1,1-dioxide and 4-cyclohexylaniline in a similar manner as described for e.g. Examples 9 and 13. 1H NMR (400 MHz, CD3CN): δ 1.19-1.44 (m, 5H), 1.64-1.84 (m, 5H), 2.31-2.40 (m, 1H), 3.38 (s, 3H), 3.72 (t, 2H), 3.90 (t, 2H), 6.67-6.72 (m, 2H), 6.80-6.85 (m, 2H), 7.05-7.14 (m, 4H), 7.19-7.24 (m, 1H), 7.75 (bs, 1H); Mass Spectrum: M+H+ 441.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582629B2
Source datasetuspto-grants-2009_09
ORD IDord-809ad94fd6ad4958bfbbb2ee21ed76a0
Source noteuspto-grants-2009_09