HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Difluoromethoxy)aniline → 4-{[4-(Difluoromethoxy)phenyl]amino}-2-methyl-5-phenylisothiazol-3(2H)-one 1,1-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Difluoromethoxy)aniline | HCID 737363 | — |
| Reactant | 4-Chloro-2-methyl-5-phenylisothiazol-3(2H)-one 1,1-dioxide | HCID 68662017 | — |
| Product | 4-{[4-(Difluoromethoxy)phenyl]amino}-2-methyl-5-phenylisothiazol-3(2H)-one 1,1-dioxide | HCID 11668023 | — |
Reaction Steps
The title compound was prepared from 4-chloro-2-methyl-5-phenylisothiazol-3(2H)-one 1,1-dioxide and 4-(difluoromethoxy)aniline in a similar manner as described for Examples 9 and 13. 1H NMR (400 MHz, CDCl3): δ 3.28 (s, 3H), 6.15-6.52 (m, 1H), 6.66-6.77 (m, 4H), 7.11-7.27 (m, 5H); Mass Spectrum: M−H+ 379.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582629B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-c1b27f95580944c09f620436891766df |
| Source note | uspto-grants-2009_09 |