反应详情

A mixture of glyoxylic acid monohydrate (4.60 g), benzotriazole (5.95 g) and benzyl carbamate (7.55 g) was heated to reflux in toluene (100 ml) for 18 h, under Dean-Stark conditions. The mixture was then allowed to cool to room temperature, and the resulting precipitate collected by filtration. This was then recrystallised from diethyl ether giving an off-white solid (11.66 g)

1. temperaturewas heated
2. filtrationthe resulting precipitate collected by filtration
3. customThis was then recrystallised from diethyl ether giving an off-white solid (11.66 g)