Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 729466Generated: October 30, 2026

Sodium Hydroxide → (5-{2-[4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl]pyrimidin-5-yl}-2H-tetrazol-2-yl)acetic acid

https://huagongshe.com/reaction/729466

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant(5-{2-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]pyrimidin-5-yl}-2H-tetrazol-2-yl)acetateHCID 86621803—
Product(5-{2-[4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl]pyrimidin-5-yl}-2H-tetrazol-2-yl)acetic acidHCID 24970225—

Reaction Steps

The title compound was prepared in a similar manner as that described for Example 3 (step 5) from ethyl ((5-{2-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]pyrimidin-5-yl}-2H-tetrazol-2-yl)acetate and aqueous NaOH.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582633B2
Source datasetuspto-grants-2009_09
ORD IDord-2943fe2384b94b7d8d29356aedcb9649
Source noteuspto-grants-2009_09