Anthranilamide → HCID 47124144, compound

Participants

Reaction Steps

To a solution of anthranilamide (2.36 g, 17.33 mmol) in 100 mL of THF at RT was added 2-chloroisonicotinoyl chloride (3.35 g, 19.04 mmol). A precipitate appeared and the reaction was heated to reflux overnight. The reaction was cooled to RT and concentrated. The precipitate was filtered and washed with H2O, CH2Cl2, and Et2O to give N-(2-carbamoyl-phenyl)-2-chloro-isonicotinamide as a light brown solid.

Provenance & Evidence