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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 729551Generated: November 1, 2026

HCID 67004364, compound → HCID 67004766, compound

https://huagongshe.com/reaction/729551

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67004364HCID 67004364—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
ProductHCID 67004766HCID 6700476673.1%

Reaction Steps

To a solution of 2-nitro-6-pyridin-2-yl-4-pyridin-3-yl-phenylamine (75 mg, 0.26 mmol) in ethyl acetate (20 mL) was added 10% palladium on carbon (50 mg). The resulting suspension was placed in a Parr hydrogenation apparatus under 40 psi hydrogen gas while shaking at ambient temperature for one hour. The catalyst was removed by filtration and the filtrate concentrated in vacuo to afford compound the title compound (50 mg, 0.19 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582641B2
Source datasetuspto-grants-2009_09
ORD IDord-898df19b43e644aa8a914d3a6fa4016c
Source noteuspto-grants-2009_09