benzyl (2R)-2-(dimethylcarbamoyl)pyrrolidine-1-carboxylate → (2R)-N,N-dimethylpyrrolidine-2-carboxamide

Participants

Reaction Steps

To the subtitle compound of step i) (4.45 g) was added palladium hydroxide (0.20 g) and methanol (50 ml). The mixture was stirred under a hydrogen atmosphere (4 bar) at room temperature for 3 h before the catalyst was filtered through celite and the solvent was evaporated to afford the subtitle compound as a solid. Yield: 2.25 g.

Provenance & Evidence