Sodium hydrosulfide hydrate → HCID 66701922, compound

Participants

Reaction Steps

Sodium hydrosulfide hydrate (2.15 g) was added to a solution of the subtitle product of step iii) (4.5 g) in DMSO (37.8 ml) and the green solution stirred for 1 h. A further aliquot of sodium hydrosulfide hydrate (0.1 g) was added and stirred for 1 h. A further aliquot of sodium hydrosulfide hydrate (0.1 g) was added and stirred for 2 h before the addition of a final aliquot of sodium hydrosulfide hydrate (0.05 g). The resulting reaction solution was used directly in the following step. The subtitle compound was also kept as a stock solution for further reaction with alkyl halides, described in Examples 112-113.

Provenance & Evidence