Hydroxyamine hydrochloride → HCID 66640723, compound

Participants

Reaction Conditions

Reaction Steps

100 mg (0.15 mmol) of 7 is dissolved in 3 ml of ethanol and 0.3 ml of water. 50 mg (0.75 mmol) of hydroxylamine hydrochloride marketed by ACROS is added and the reaction medium is heated for 18 hours at 90° C. The solvents are evaporated off under reduced pressure (2 kPa) and the crude residue is purified by chromatography on silicagel eluting with a CH2Cl2/MeOH mixture 90:10. 30 mg (36%) of expected product is obtained in the form of a colourless resin.

Provenance & Evidence