HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-pyridinecarbonitrile → 4-(4-Amino-2-fluorophenoxy)pyridine-2-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-pyridinecarbonitrile | HCID 693342 | — |
| Reactant | Phenol, 4-amino-2-fluoro- | HCID 2735918 | — |
| Reactant | 4-(3-Aminophenoxy)pyridine-2-carboxamide | HCID 23137229 | — |
| Product | 4-(4-Amino-2-fluorophenoxy)pyridine-2-carbonitrile | HCID 57833239 | — |
Reaction Steps
4-(4-Amino-2-fluorophenoxy)pyridine-2-carbonitrile (2H) was prepared by a method analogous to that described for 4-(3-aminophenoxy)pyridine-2-carboxamide (2C), starting from 4-amino-2-fluorophenol and 4-chloro-2-cyanopyridine, MS ES: 230 (M+H)+, calcd 230, RT=2.18 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582645B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-5633d2ecb382444f9c95dc325259996d |
| Source note | uspto-grants-2009_09 |