HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → HCID 57833259, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 136183340 | HCID 136183340 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 57833259 | HCID 57833259 | — |
Reaction Steps
To a solution of Step 2 product (1 equiv) in DMF is added 1,2-dibromoethane (1 equiv) and K2CO3 (3 equiv). The mixture is refluxed overnight. After cooling to rt, the mixture is diluted with EtOAc and washed sequentially with 1N NaOH, water and brine. The organic layer is dried (Na2SO4) and concentrated to afford a crude product which is to be used in next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582645B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-cc2662c9c65f45c8827bf05daaf804ab |
| Source note | uspto-grants-2009_09 |