4-(2-Chloro-pyridin-4-yloxy)-phenylamine → HCID 136183341, compound

Participants

Role	Name	HCID	Charge
Reactant	4-(2-Chloro-pyridin-4-yloxy)-phenylamine	HCID 57833430	—
Reactant	4-(2-Amino-6-chloro-4-pyrimidinyl)phenyl 1,1-dimethylethyl carbonate	HCID 57833571	—
Product	HCID 136183341	HCID 136183341	—

Reaction Steps

This material was prepared by a method analogous to that described for Example 1, starting from the product from 4-(2-amino-6-chloropyrimidin-4-yl)phenyl tert-butyl carbonate and Intermediate 2R. 1H NMR (DMSO-d6) δ 9.79 (s, 1H), 9.25 (s, 1H), 8.22 (d, 1H), 7.86 (m, 2H), 7.74 (m, 2H), 7.09 (m, 2H), 6.95 (m, 2H), 6.80 (m, 2H), 6.39 (s, 1H), 6.23 (s, 2H); MS ES 406 (M+H)+, calcd 406, RT=2.74 min.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07582645B2
Source dataset	uspto-grants-2009_09
ORD ID	ord-f5fb1d5d753044ee9fa72a8de402c98a
Source note	uspto-grants-2009_09