HCID 69053543, compound → Hydrochloric Acid

Participants

Reaction Steps

Following the above procedure described for compound 4a, the reaction of 3,5-bis(thiophen-2-ylmethylene)-piperidin-4-one with V. HCl (X=CO, T=OH, Y=O, o=2, Z=N(C2H5)2) (0.015 mol) afforded 9a, m.p. 193-194° in 82% yield. δ (CDCl3): 1.44-1.47 (t, 6H, 2×CH3), 3.17-3.31 (m, 4H, 2×NCH2), 3.56 (br s, 2H, NCH2), 4.53 (t, 2H, OCH2), 4.93 (br s, 4H, 2×NCH2), 6.75-6.77 (d, 2H, C2—H &C6—H), 7.18-7.19 (t, 2H, 2×C3′—H), 7.38-7.40 (d, 4H, C3—H, C5—H & 2×C4′—H), 7.66-7.67 (d, 2H, C2′—H), 12.67 (s, 1H, NH). Found C, 59.90%; H, 5.76%; N, 4.81%. C28H31ClN2O3S2.H2O requires C, 59.92%; H, 5.56%; N, 4.99%.

Provenance & Evidence