HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-pyridinecarbonitrile → 4-(4-Amino-3-fluorophenoxy)picolinonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-pyridinecarbonitrile | HCID 693342 | — |
| Reactant | 4-Amino-3-fluorophenol | HCID 2735919 | — |
| Reactant | 4-(3-Aminophenoxy)pyridine-2-carboxamide | HCID 23137229 | — |
| Product | 4-(4-Amino-3-fluorophenoxy)picolinonitrile | HCID 55156658 | — |
Reaction Steps
4-(4-Amino-3-fluorophenoxy) pyridine-2-carbonitrile (2G) was prepared by a method analogous to that described for 4-(3-aminophenoxy) pyridine-2-carboxamide (2C), starting from 4-amino-3-fluorophenol and 4-chloro-2-cyanopyridine, MS ES: 230 (M+H)+, calcd 230, RT=2.85 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582646B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-be1dd4428b6d443e8aac397207aeb93e |
| Source note | uspto-grants-2009_09 |