2-Bromo-4-methylpyridine → HCID 11119933, compound
Reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][N:3]=1.ClC1C=C(C[C:17]([C:19]2[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=2)=[O:18])C=CN=1>>[Br:1][C:2]1[CH:7]=[C:6]([CH2:8][C:17]([C:19]2[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=2)=[O:18])[CH:5]=[CH:4][N:3]=1Participants
3
Procedure
21c was prepared from 2-bromo-4-methylpyridine (9.6 g; 56 mmol) using the method described in the synthesis of 21a.
Sources & evidence
- ORD record
- ord-250a344887e14724a7882ae80853825a
- Source dataset
- uspto-grants-2009_09
- Patent number
- US07582660B2
Reaction notes
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