1-(4-Fluorophenyl)-2-(2-fluoropyridin-4-yl)ethanone → 1-(2-Fluoropyridin-4-yl)-2-(4-fluorophenyl)ethane-1,2-dione-1-oxime

HRID 730045Notes

Reaction equation

HRID 730045 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:17])[CH2:9][C:10]2[CH:15]=[CH:14][N:13]=[C:12]([F:16])[CH:11]=2)=[CH:4][CH:3]=1.ClC1C=C(C(=[N:35][OH:36])C(C2C=CC(F)=CC=2)=O)C=CN=1>>[F:16][C:12]1[CH:11]=[C:10]([C:9](=[N:35][OH:36])[C:8]([C:5]2[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=2)=[O:17])[CH:15]=[CH:14][N:13]=1

Participants

3

Reactant 2

HCID 110317691-(4-Fluorophenyl)-2-(2-fluoropyridin-4-yl)ethanoneHCID 136335779HCID 136335779, compound

Product 1

HCID 1363357801-(2-Fluoropyridin-4-yl)-2-(4-fluorophenyl)ethane-1,2-dione-1-oxime

Procedure

22b was prepared from 21b (10.0 g; 43 mmol) using the method described in the synthesis of 22a.

Sources & evidence

ORD record
ord-a16370de0c56421189d440b492f236d2
Source dataset
uspto-grants-2009_09
Patent number
US07582660B2

Reaction notes

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