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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 730053Generated: October 30, 2026

4-(2-Chloropyridin-4-yl)-5-(4-fluorophenyl)-1,3-dihydroimidazole-2-thione → 4-(4-Fluorophenyl)-5-(2-isopropoxypyridin-4-yl)-1,3-dihydroimidazole-2-thione

https://huagongshe.com/reaction/730053

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Chloropyridin-4-yl)-5-(4-fluorophenyl)-1,3-dihydroimidazole-2-thioneHCID 10859727—
Reactant2-Amino-1-(4-fluorophenyl)-2-(2-isopropoxypyridin-4-yl)ethanone hydrochlorideHCID 69054649—
Product4-(4-Fluorophenyl)-5-(2-isopropoxypyridin-4-yl)-1,3-dihydroimidazole-2-thioneHCID 10860473—

Reaction Steps

24c was prepared from 23c (2.5 g; 7.6 mmol) using the method described in the synthesis of 24a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582660B2
Source datasetuspto-grants-2009_09
ORD IDord-df38742bff624a119bb148051adfa229
Source noteuspto-grants-2009_09