HCID 178418582, compound → HCID 178488112, compound

Participants

Reaction Steps

A suspension of 25a (0.1 g; 0.25 mmol) in methanolic NaOCH3 solution (30%, 2 ml) was diluted with methanol (5 ml) and stirred under reflux for 13 h. The reaction mixture was diluted with H2O and the aqueous solution was extracted with CH2Cl2 (3×). The combined organic extract was washed with saturated NaCl solution, dried over Na2SO4 and concentrated. The oily residue was purified by column chromatography (SiO2 60, CH2Cl2/ethyl acetate 1+1).

Provenance & Evidence