HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-t-Butylbenzenesulfonyl chloride → N-[4-Bromo-2-(pyridine-4-carbonyl)-phenyl]4-tert-butyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-t-Butylbenzenesulfonyl chloride | HCID 139882 | — |
| Reactant | (2-Amino-5-bromophenyl)(pyridin-4-yl)methanone | HCID 13549724 | — |
| Product | N-[4-Bromo-2-(pyridine-4-carbonyl)-phenyl]4-tert-butyl-benzenesulfonamide | HCID 10412561 | — |
Reaction Steps
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 138 mg of (2-Amino-5-bromo-phenyl)-pyridin-4-yl-methanone and 116 mg of 4-tert-butyl-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 1.27 (3, 9H), 7.41 (m, 3H), 7.50 (dd, 2H, J=4.8 Hz, 1.6 Hz), 7.67-72 (m, 4H), 8.85 (d, 2H, J=6 Hz), 10.19 (s, 1H). MS: m/z 473.9 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582661B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-682a56d19f2e4669bb6b7d3eb5bca9ff |
| Source note | uspto-grants-2009_09 |