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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 730110Generated: October 30, 2026

4-t-Butylbenzenesulfonyl chloride → HCID 10410347, compound

https://huagongshe.com/reaction/730110

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-t-Butylbenzenesulfonyl chlorideHCID 139882—
ReactantHCID 22327319HCID 22327319—
ProductHCID 10410347HCID 10410347—

Reaction Steps

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 116 mg of (2-amino-4-chloro-phenyl)-pyridin-4-yl-methanone and 116 mg of 4-tert-butyl-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 1.30 (s, 9H), 7.04 (d, 1 H, J=8.4 Hz), 7.25 (d, 1H, J=8.4 Hz), 7.45-7.52 (m, 4H), 7.74 (dd, 2H, J=8.8 Hz, 1.6 Hz), 7.52 (dd, 2H, J=4,4 Hz, 1.6 Hz), 7.78 (m, 2H), 7.84 (d, 1.6 Hz), 8.84 (d, 2H, J=5.6 Hz), 10.61 (s, 1H). MS: m/z 429.0 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582661B2
Source datasetuspto-grants-2009_09
ORD IDord-24011147ef6d43268154689e19dc4096
Source noteuspto-grants-2009_09