HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Amino-5-chlorophenyl)-pyridin-4-yl methanone → N-(4-Chloro-2-isonicotinoylphenyl)-4-isopropoxybenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Amino-5-chlorophenyl)-pyridin-4-yl methanone | HCID 10214538 | — |
| Reactant | 4-(Propan-2-yloxy)benzene-1-sulfonyl chloride | HCID 22327297 | — |
| Product | N-(4-Chloro-2-isonicotinoylphenyl)-4-isopropoxybenzenesulfonamide | HCID 10432875 | — |
Reaction Steps
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 116 mg of (2-Amino-5-chloro-phenyl)-pyridin-4-yl-methanone and 117 mg of 4-Isopropoxy-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 1.01 (d, 6H, J=5.6 Hz), 4.27 (m, 1H), 6.51 (d, 2H, J=8.8 Hz), 6.87 (d, 1H, J=8.8 Hz), 7.15-7.25 (m, 4H), 7.60 (d, 2H, J=6.0 Hz), 8.64 (d, 2H, J=6 Hz), 9.60 (s, 1H). MS: m/z 431.9 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07582661B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-461bbc17a2874001b79ab57c944c309c |
| Source note | uspto-grants-2009_09 |