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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 730140Generated: October 29, 2026

4-t-Butylbenzenesulfonyl chloride → 4-tert-Butyl-N-[4-chloro-2-(6-methyl-pyridine-2-carbonyl)-phenyl]-benzenesulfonamide

https://huagongshe.com/reaction/730140

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-t-Butylbenzenesulfonyl chlorideHCID 139882—
Reactant(2-Amino-5-chloro-phenyl)-(6-methyl-pyridin-2-yl)-methanoneHCID 22327312—
Product4-tert-Butyl-N-[4-chloro-2-(6-methyl-pyridine-2-carbonyl)-phenyl]-benzenesulfonamideHCID 10433490—

Reaction Steps

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using (2-Amino-5-chloro-phenyl)-(6-methyl-pyridin-2-yl)-methanone and 4-tert-Butyl-benzenesulfonyl chloride and purified by HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07582661B2
Source datasetuspto-grants-2009_09
ORD IDord-a8310aa1278544c795865a0e78f72589
Source noteuspto-grants-2009_09